This randomized clinical trial tested the impact of Mano a Mano-Mujer (MM-M), an adaptation of the SEPA intervention for Chilean women, on HIV prevention and depressive symptoms. A total of 400 women in Santiago Chile were enrolled in the study and were randomized into either experimental intervention or a control group. The intervention consisted of six sessions delivered in small groups. Face-to-face interviews were conducted at baseline and at 3-month follow-up.
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