Cherie Stabler, Ph.D.

Assistant Professor

Biomedical Engineering
McArthur Engineering Annex, Room 204
University of Miami
P.O. Box 248294
Coral Gables, FL 33124-0620
and
Diabetes Research Insitute
MillerSchoolof Medicine
Universityof Miami
1450 10th Avenue, Rm 3016
Miami, FL 33136
(305) 243-9768
cstabler@miami.edu

 

EDUCATION TEACHING RESEARCH PUBLICATIONS EXPERIENCE HONORS  OPPORTUNITIES

EDUCATION:

• B. S. Chemical Engineering-Bioengineering, Florida State University, Tallahassee, FL., 1998.
  
• Ph.D. Biomedical Engineering, Georgia Institute of Technology/Emory University, Atlanta, GA, 2004.

TEACHING:
Courses to be announced.

RESEARCH:
    Our laboratory is focused on the areas of tissue engineering, biomaterials, and noninvasive monitoring.
    One aspect of our research is designing and developing various cell encapsulation techniques and evaluating how these barriers can protect transplanted cells against the vigorous immunological and inflammatory responses of the host.  The primary application of this research is within the field of diabetes, where insulin-producing cells, or islets, require protection from the host during transplantation.
    In addition, our laboratory is investigating the application of conjugation techniques to tether agents to the polymer layers in order to generate implants capable of “actively” modulating the interaction between the host and implanted cells.
    Finally, our laboratory uses NMR imaging and spectroscopy to develop methods for the noninvasive monitoring and assessment of tissue engineered implants, such as insulin-producing cells.  Noninvasive monitoring of cells after they are transplanted is significant for understanding their function and remodeling over time. It is also important in determining the link between implantation and endpoint physiologic effects.

PUBLICATIONS:

Sun, X-L, Stabler, CL, Cazalis, CS, and Chaikof, EL, Carbohydrate and Protein Immobilization onto Solid Surfaces by Sequential Diels-Alder and Azide-Alkyne Cycloadditions, Bioconjugate Chemistry, 17 (1), pp.52-57, (2006).

Stabler, CL, Long, RC, Constantinidis, I., and Sambanis, A., In vivo noninvasive monitoring of a tissue engineered construct using 1H NMR spectroscopy, Cell Transplantation, 14(2-3), pp.139-49 (2005).

Stabler, CL, Long, RC, Constantinidis, I., and Sambanis, A., Noninvasive measurement of viable cell number in tissue engineered constructs in vitro using 1H NMR spectroscopy, Tissue Engineering, 11 (3-4), pp. 404-414 (2005).

Oca-Cossio, J, Mao, H, Khokhlova, N, Kennedy, CM, Kennedy, JW, Stabler, CL, Hao, E Sambanis, A, Simpson NE, Constantinidis, I, Magnetically labeled insulin secreting cells, Biochemical and Biophysical Research Communications, 319, pp. 569-575, (2004).

Simpson, NE, Stabler, CL, Simpson, C., Sambanis, A., and Constantinidis, I., The role of the CaCl2-guluronic acid interaction on alginate encapsulated betaTC3 cells, Biomaterials, 25, pp. 2603-2610 (2004).

Sambanis, A., Tang, S.-C., Cheng, S.-Y., Stabler, CL, Long, RC, and Constantinidis, I., Core technologies in tissue engineering and their application to the bioartificial pancreas, in Tissue Engineering for Therapeutic Use 6, (Ikada Y., Umakoshi, Y. and Hotta T., Editors), pp. 5-18, Elsevier, Boston MA (2002).

Stabler, CL, Sambanis, A., and Constantinidis, I., Effects of alginate composition on the growth and overall metabolic activity of bTC3 cells, Ann NY Acad Sci, 961, pp.130-133 (2002).

Constantinidis, I., Stabler, CL., Long, RC, and Sambanis, A., Noninvasive monitoring of a retrievable bioartificial pancreas in vivo, Ann NY Acad Sci, 961, pp. 298-301, (2002).

Stabler, CL, Wilks, K., Sambanis, A., and Constantinidis, I., The effects of alginate composition on encapsulated bTC3 cells, Biomaterials, 22, pp. 1301-1310 (2001).

EXPERIENCE:

• Assistant Professor, Department of Biomedical Engineering, University of Miami, 2006-present
  
• Director, Tissue Engineering Laboratory, Diabetes Research Institute, School of Medicine, University of Miami, 2006-present
  
• Assistant Professor (secondary), Department of Surgery, School of Medicine, University of Miami, 2006 to present
  
• Postdoctoral Fellow, Department of Surgery, Emory University, 2004 to 2006                        
  
• Graduate Research Assistant, Department of Biomedical Engineering, Georgia Institute of Technology & Emory University, 1998-2004
  
• Research Associate Intern, Advanced Tissue Sciences Co., La Jolla, CA, 2000
  

HONORS: 

• Juvenile Diabetes Research Foundation Individual Postdoctoral Fellowship
  
• NIH Ruth L. Kirschstein National Research Service Award Individual Postdoctoral Fellowship
  
• The Georgia Institute of Technology George Graduate Fellowship
  
• NIH Graduate Training Grant Recipient
  
• Medtronic Corporation Graduate Research Fellowship
  
• Florida State University Most Promising Alumni
  

 

OPPORTUNITIES:

Research and design projects are available to highly motivated graduate and undergraduate students in the Tissue Engineering Laboratory at the Diabetes Research Institute on the School of Medicine campus. Please email Dr. Stabler for more information.